Reaction Details |
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Target | Thromboxane A2 receptor |
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Ligand | BDBM50283060 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_209587 |
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EC50 | 3110±n/a nM |
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Citation | Burk, RM; Gac, TS; Garst, ME; Gibson, LL; Krauss, AH; Protzman, CE; Woodward, DF Synthesis of a novel series of 3-oxo-2,4-dioxobicyclo[3.2.1]octanes: additional evidence for two thromboxane receptor subtypes. Bioorg Med Chem Lett4:2103-2106 (1994) Article |
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More Info.: | Get all data from this article, Assay Method |
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Thromboxane A2 receptor |
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Name: | Thromboxane A2 receptor |
Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
Type: | Enyzme |
Mol. Mass.: | 37445.28 |
Organism: | Homo sapiens (Human) |
Description: | P21731 |
Residue: | 343 |
Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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BDBM50283060 |
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n/a |
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Name | BDBM50283060 |
Synonyms: | (Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-3-oxo-2,4-dioxa-bicyclo[3.2.1]oct-6-yl]-hept-5-enoic acid amide | CHEMBL441620 |
Type | Small organic molecule |
Emp. Form. | C21H33NO5 |
Mol. Mass. | 379.4904 |
SMILES | CCCCCC(O)\C=C\[C@H]1[C@H]2C[C@H](OC(=O)O2)[C@@H]1C\C=C/CCCC(N)=O |
Structure |
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