| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50283060 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_209743 |
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| EC50 | 58±n/a nM |
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| Citation |  Burk, RM; Gac, TS; Garst, ME; Gibson, LL; Krauss, AH; Protzman, CE; Woodward, DF Synthesis of a novel series of 3-oxo-2,4-dioxobicyclo[3.2.1]octanes: additional evidence for two thromboxane receptor subtypes. Bioorg Med Chem Lett4:2103-2106 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | TA2R_RAT | TXA2/PGH2 | Tbxa2r | Thromboxane A2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36943.05 |
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| Organism: | RAT |
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| Description: | Thromboxane A2 TBXA2R RAT::P34978 |
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| Residue: | 341 |
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| Sequence: | MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRS
SFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLL
LGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSW
CFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEM
MVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQIL
DPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
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| BDBM50283060 |
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| n/a |
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| Name | BDBM50283060 |
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| Synonyms: | (Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-3-oxo-2,4-dioxa-bicyclo[3.2.1]oct-6-yl]-hept-5-enoic acid amide | CHEMBL441620 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H33NO5 |
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| Mol. Mass. | 379.4904 |
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| SMILES | CCCCCC(O)\C=C\[C@H]1[C@H]2C[C@H](OC(=O)O2)[C@@H]1C\C=C/CCCC(N)=O |
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| Structure | 
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