| Reaction Details |
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 | Report a problem with these data |
| Target | Substance-K receptor |
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| Ligand | BDBM50283250 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_142709 |
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| IC50 | 1370±n/a nM |
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| Citation |  Horwell, DC; Nichols, PD; Roberts, E Methionine replacements in biologically active peptides Bioorg Med Chem Lett4:2263-2266 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Substance-K receptor |
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| Name: | Substance-K receptor |
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| Synonyms: | NK2R_MESAU | Neurokinin 2 receptor | Neurokinin NK2 | TAC2R | TACR2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43436.75 |
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| Organism: | HAMSTER |
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| Description: | P51144 |
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| Residue: | 384 |
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| Sequence: | MGGRAIVTDTNIFSGLESNTTGVTAFSMPAWQLALWATAYLGLVLVAVTGNATVIWIILA
HERMRTVTNYFIINLALADLCMAAFNATFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
IYSMTAIAADRYMAIVHPFQPRLSAPITKATIAGIWLVALALASPQCFYSTITVDQGATK
CVVAWPNDNGGKMLLLYHLVVFVLVYFLPLVVMFVAYSVIGLTLWKRAVPRHQAHGANLR
HLHAKKKFVKAMVLVVLTFAICWLPYHLYFILGSFQKDIYYRKFIQQVYLALFWLAMSST
MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDRLELTRTPSLSRRVNRCHTKETLFMT
ADMTHSEATNGQVGSPQDVEPAAP
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| BDBM50283250 |
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| n/a |
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| Name | BDBM50283250 |
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| Synonyms: | (S)-2-[2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-4-carbamoyl-butyrylamino)-4-carbamoyl-butyrylamino]-3-phenyl-propionylamino}-3-phenyl-propionylamino)-acetylamino]-4-methyl-pentanoic acid ((E)-(S)-1-carbamoyl-hex-4-enyl)-amide | CHEMBL449091 |
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| Type | Small organic molecule |
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| Emp. Form. | C45H64N10O10 |
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| Mol. Mass. | 905.0507 |
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| SMILES | C\C=C\CC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(C)=O)C(N)=O |
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| Structure | 
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