| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50283398 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_201299 |
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| Ki | 2.5±n/a nM |
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| Citation |  Cain, GA; Christos, TE; Eyermann, CJ; Gilligan, PJ; Grigoriadis, DE; Johnson, AL; Tam, S Novel conformationally restricted aromatic piperidines as selective sigma receptor ligands Bioorg Med Chem Lett4:329-334 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50283398 |
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| n/a |
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| Name | BDBM50283398 |
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| Synonyms: | (1-Benzyl-piperidin-4-yl)-(3-phenyl-prop-2-ynyl)-amine; compound with (E)-but-2-enedioic acid | CHEMBL115934 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N2 |
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| Mol. Mass. | 304.4287 |
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| SMILES | C(NC1CCN(Cc2ccccc2)CC1)C#Cc1ccccc1 |
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| Structure | 
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