| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50283867 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_85844 (CHEMBL692952) |
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| Ki | 0.740000±n/a nM |
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| Citation |  Stark, H; Krause, M; Arrang, JM; Ligneau, X; Schwartz, JC; Schunack, W Unsymmetrically substituted guanidines as potent histamine H3-receptor antagonists Bioorg Med Chem Lett4:2907-2912 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48753.61 |
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| Organism: | GUINEA PIG |
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| Description: | HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35 |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
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| BDBM50283867 |
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| n/a |
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| Name | BDBM50283867 |
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| Synonyms: | CHEMBL98165 | N-Cyclohexylmethyl-N'-[3-(1H-imidazol-4-yl)-propyl]-guanidine |
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| Type | Small organic molecule |
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| Emp. Form. | C14H25N5 |
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| Mol. Mass. | 263.3818 |
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| SMILES | N=C(NCCCc1cnc[nH]1)NCC1CCCCC1 |
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| Structure | 
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