| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM50283962 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_49409 (CHEMBL658770) |
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| IC50 | 4000±n/a nM |
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| Citation |  Horwell, DC; Lennon, IC; Roberts, E Alternative strategies towards the identification of chemical lead compounds by rational design Bioorg Med Chem Lett4:525-530 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49676.37 |
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| Organism: | RAT |
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| Description: | Cholecystokinin central 0 RAT::P30551 |
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| Residue: | 444 |
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| Sequence: | MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQI
LLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLK
DFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAAT
WCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVM
VVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQL
SSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAE
KHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEE
DGRTIRALLSRYSYSHMSTSAPPP
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| BDBM50283962 |
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| n/a |
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| Name | BDBM50283962 |
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| Synonyms: | (S)-1-Benzyl-3,5-bis-(1H-indol-3-ylmethyl)-piperidin-4-one | CHEMBL347058 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H29N3O |
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| Mol. Mass. | 447.5708 |
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| SMILES | O=C1C(Cc2c[nH]c3ccccc23)CN(Cc2ccccc2)C[C@@H]1Cc1c[nH]c2ccccc12 |
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| Structure | 
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