Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50284922 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_79465 |
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Ki | 1.2±n/a nM |
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Citation | Randad, RS; Lubkowska, L; Bhat, TN; Munshi, S; Gulnik, SV; Yu, B; Erickson, JW Symmetry-based HIV Protease inhibitors: rational design of 2-methylbenzamides as novel P2/P2′ ligands Bioorg Med Chem Lett5:1707-1712 (1995) Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50284922 |
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n/a |
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Name | BDBM50284922 |
Synonyms: | 1N-[1-benzyl-2,3-dihydroxy-4-(3-hydroxy-2-methylphenylcarboxamido)-5-phenyl-(1S,2R,3S,4S)-pentyl]-3-hydroxy-2-methylbenzamide | CHEMBL299869 |
Type | Small organic molecule |
Emp. Form. | C34H36N2O6 |
Mol. Mass. | 568.6594 |
SMILES | Cc1c(O)cccc1C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cccc(O)c1C |
Structure |
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