| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
|---|
| Ligand | BDBM10755 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1651 |
|---|
| EC50 | 8.5±n/a nM |
|---|
| Citation |  Macor, JE; Blank, DH; Desai, K; Fox, CB; Koe, BK; Lebel, LA; Post, RJ; Schmidt, AW; Schulz, DW; Seymour, PA 5-cyano-1-[3-(N-methylpyrrolidin-2R-ylmethyl)indol-5-yl] benzimidazole (CP-161,242): A potent, centrally active 5-HT1D receptor agonist and benzodiazepine partial agonist Bioorg Med Chem Lett5:2391-2396 (1995) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 1D |
|---|
| Name: | 5-hydroxytryptamine receptor 1D |
|---|
| Synonyms: | 5-HT1D | 5-hydroxytryptamine receptor 1D | 5HT1D_CAVPO | HTR1D | Serotonin 1d (5-HT1d) receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 41780.38 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | 5-HT1D HTR1D GUINEA PIG::Q60484 |
|---|
| Residue: | 376 |
|---|
| Sequence: | MSPPNQSEEGLPQEASNRSLNATETPGDWDPGLLQALKVSLVVVLSIITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAGAMIAAVWVISICISIPPLFWRQAQ
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYSRIYRAARSRILNPPSLSGKRFT
TAHLITGSAGSSLCSLNPSLHEGHMHPGSPLFFNHVRIKLADSVLERKRISAARERKATK
TLGIILGAFIVCWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNE
DFRQAFQKVVHFRKAS
|
|
|
|---|
| BDBM10755 |
|---|
| n/a |
|---|
| Name | BDBM10755 |
|---|
| Synonyms: | 14C-5-hydroxy tryptamine creatinine disulfate | 2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid) | 5-HT | 5-Hydroxy Tryptamine | 5-hydroxy tryptamine creatinine disulfate | CHEMBL535832 | Serotonin | [3H]-5-HT |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H12N2O |
|---|
| Mol. Mass. | 176.2151 |
|---|
| SMILES | NCCc1c[nH]c2ccc(O)cc12 |
|---|
| Structure | 
|
|---|
Search and Browse
