| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50285993 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_155158 |
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| Ki | 1.7±n/a nM |
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| Citation |  Holms, JH; Davidsen, SK; Sheppard, GS; Carrera, GM; Curtin, NL; Heyman, HR; Pireh, D; Steinman, DH; Albert, DH; Conway, RG; Luo, G; Magoc, TJ; Tapang, P; Rhein, DA; Summers, JB Discovery and optimization of indole pyrrolothiazole paf antagonists Bioorg Med Chem Lett5:2903-2908 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Protein |
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| Mol. Mass.: | 39005.63 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 342 |
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| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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| BDBM50285993 |
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| n/a |
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| Name | BDBM50285993 |
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| Synonyms: | 6-(4-Fluoro-phenoxy)-3-(3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazole-7-carbonyl)-indole-1-carboxylic acid dimethylamide | CHEMBL99528 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H23FN4O3S |
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| Mol. Mass. | 526.581 |
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| SMILES | CN(C)C(=O)n1cc(C(=O)c2ccn3C(SCc23)c2cccnc2)c2ccc(Oc3ccc(F)cc3)cc12 |
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| Structure | 
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