| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
|---|
| Ligand | BDBM50286165 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_49403 |
|---|
| IC50 | 420±n/a nM |
|---|
| Citation |  Holladay, MW; Bennett, MJ; Bai, H; Ralston, JW; Kerwin, JF; Stashko, M; Miller, TR; O'Neill, AB; Nadzan, AM; Brioni, J; Lin, CW Amino acid-derived piperidides as novel CCKB ligands with anxiolytic-like properties Bioorg Med Chem Lett5:3057-3062 (1995) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cholecystokinin receptor type A |
|---|
| Name: | Cholecystokinin receptor type A |
|---|
| Synonyms: | CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 48229.77 |
|---|
| Organism: | Cavia porcellus |
|---|
| Description: | n/a |
|---|
| Residue: | 430 |
|---|
| Sequence: | MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNT
LVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYF
MGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYS
NLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGI
KFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRS
SSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLL
SYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSY
SHMSTSAPPP
|
|
|
|---|
| BDBM50286165 |
|---|
| n/a |
|---|
| Name | BDBM50286165 |
|---|
| Synonyms: | 1-{1-((R)-Benzyloxymethyl)-2-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-2-oxo-ethyl}-3-m-tolyl-urea | CHEMBL102879 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H32FN3O4 |
|---|
| Mol. Mass. | 517.5912 |
|---|
| SMILES | Cc1cccc(NC(=O)N[C@H](COCc2ccccc2)C(=O)N2CCC(CC2)C(=O)c2ccc(F)cc2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
