| Reaction Details |
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 | Report a problem with these data |
| Target | Interstitial collagenase |
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| Ligand | BDBM50286351 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_101763 |
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| Ki | >100±n/a nM |
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| Citation |  Wahl, RC; Pulvino, TA; Mathiowetz, AM; Ghose, AK; Johnson, JS; Delecki, D; Cook, ER; Gainor, JA; Gowravaram, MR; Tomczuk, BE Hydroxamate inhibitors of human gelatinase B (92 kDa) Bioorg Med Chem Lett5:349-352 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Interstitial collagenase |
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| Name: | Interstitial collagenase |
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| Synonyms: | CLG | Fibroblast collagenase | MMP1 | MMP1_HUMAN | Matrix metalloproteinase-1 | Matrix metalloproteinase-1 (MMP-1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 54010.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P03956 |
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| Residue: | 469 |
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| Sequence: | MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPV
VEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIEN
YTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGN
LAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSY
TFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDR
FYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGY
PKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFP
GIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
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| BDBM50286351 |
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| n/a |
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| Name | BDBM50286351 |
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| Synonyms: | (R)-2-(4-Benzyloxy-butyl)-N*4*-hydroxy-N*1*-methylcarbamoylmethyl-succinamide | CHEMBL117296 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H27N3O5 |
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| Mol. Mass. | 365.4241 |
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| SMILES | CNC(=O)CNC(=O)[C@H](CCCCOCc1ccccc1)CC(=O)NO |
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| Structure | 
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