Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50286551 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_195356 |
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IC50 | 8.1±n/a nM |
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Citation | Young, SD; Amblard, MC; Britcher, SF; Grey, VE; Tran, LO; Lumma, WC; Huff, JR; Schleif, WA; Emini, EE; O'Brien, JA; Pettibone, DJ 2-Heterocyclic indole-3-sulfones as inhibitors of HIV-1 reverse transcriptase Bioorg Med Chem Lett5:491-496 (1995) Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50286551 |
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n/a |
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Name | BDBM50286551 |
Synonyms: | 2-(3-Benzenesulfonyl-5-chloro-1H-indol-2-yl)-4,5,6,7-tetrahydro-1H-benzoimidazole | CHEMBL147790 |
Type | Small organic molecule |
Emp. Form. | C21H18ClN3O2S |
Mol. Mass. | 411.905 |
SMILES | Clc1ccc2[nH]c(-c3nc4CCCCc4[nH]3)c(c2c1)S(=O)(=O)c1ccccc1 |
Structure |
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