| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor alpha |
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| Ligand | BDBM50286564 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_195193 |
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| EC50 | >10000±n/a nM |
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| Citation |  Chandraratna, RA; Gillett, SJ; Song, TK; Attard, J; Vuligonda, S; Garst, ME; Arefieg, T; Gil, DW; Wheeler, L Synthesis and pharmacological activity of conformationally restricted, acetylenic retinoid analogs Bioorg Med Chem Lett5:523-527 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor alpha |
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| Name: | Retinoic acid receptor alpha |
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| Synonyms: | NR1B1 | Nuclear receptor subfamily 1 group B member 1 | RAR-alpha | RARA | RARA_HUMAN | Retinoic acid receptor alpha | Retinoic acid receptor alpha/Retinoid X receptor alpha | Retinoid X receptor gamma/retinoic acid receptor alpha | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50778.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1466191 |
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| Residue: | 462 |
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| Sequence: | MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
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| BDBM50286564 |
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| n/a |
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| Name | BDBM50286564 |
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| Synonyms: | 3-[(E)-4-(2,6,6-Trimethyl-cyclohex-1-enyl)-but-3-en-1-ynyl]-benzoic acid | CHEMBL150583 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22O2 |
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| Mol. Mass. | 294.3875 |
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| SMILES | CC1=C(\C=C\C#Cc2cccc(c2)C(O)=O)C(C)(C)CCC1 |c:1| |
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| Structure | 
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