| Reaction Details |
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 | Report a problem with these data |
| Target | Stromelysin-1 |
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| Ligand | BDBM50286565 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_102085 |
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| Ki | 240±n/a nM |
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| Citation |  Esser, CK; Kopka, IE; Durette, PL; Harrison, RK; Niedzwiecki, LM; Izquierdo-Martin, M; Stein, RL; Hagmann, WK Inhibition of matrix metalloproteinases by N-carboxyalkyl peptides containing extended alkyl residues At P1' Bioorg Med Chem Lett5:539-542 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Stromelysin-1 |
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| Name: | Stromelysin-1 |
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| Synonyms: | MMP-3 | MMP3 | MMP3_HUMAN | Matrix metalloproteinase (2 and 3) | Matrix metalloproteinase 3 | Matrix metalloproteinase-3 | Matrix metalloproteinase-3 (MMP-3) | Matrix metalloproteinase-3 (MMP3) | SL-1 | STMY1 | Stromelysin 1 | Transin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 53973.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08254 |
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| Residue: | 477 |
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| Sequence: | MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPV
VKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVN
YTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNV
LAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLY
HSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVS
TLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQF
WAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEP
GFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC
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| BDBM50286565 |
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| n/a |
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| Name | BDBM50286565 |
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| Synonyms: | (R)-2-[(S)-10-Amino-1-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-decylamino]-propionic acid | CHEMBL151047 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H44N4O4 |
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| Mol. Mass. | 476.652 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](CCCCCCCCCN)N[C@H](C)C(O)=O)C(=O)Nc1ccccc1 |
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| Structure | 
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