| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM3414 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_159623 |
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| IC50 | 1.4±n/a nM |
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| Citation |  Kaldor, SW; Appelt, K; Fritz, JE; Hammond, M; Crowell, TA; Baxter, AJ; Hatch, SD; Wiskerchen, M; Muesing, MA A systematic study of P1–P3 spanning sidechains for the inhibition of HIV-1 protease Bioorg Med Chem Lett5:715-720 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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| BDBM3414 |
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| n/a |
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| Name | BDBM3414 |
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| Synonyms: | (2S)-N-[(2S,3R)-4-[2-(tert-butylcarbamoyl)phenyl]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinolin-2-ylformamido)butanediamide | LY289612 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H39N5O5 |
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| Mol. Mass. | 609.7147 |
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| SMILES | CC(C)(C)NC(=O)c1ccccc1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1 |r| |
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| Structure | 
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