| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50213827 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_159623 (CHEMBL881019) |
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| IC50 | <0.250000±n/a nM |
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| Citation |  Kaldor, SW; Appelt, K; Fritz, JE; Hammond, M; Crowell, TA; Baxter, AJ; Hatch, SD; Wiskerchen, M; Muesing, MA A systematic study of P1–P3 spanning sidechains for the inhibition of HIV-1 protease Bioorg Med Chem Lett5:715-720 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50213827 |
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| n/a |
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| Name | BDBM50213827 |
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| Synonyms: | CHEMBL351834 |
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| Type | Small organic molecule |
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| Emp. Form. | C42H52N6O5S |
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| Mol. Mass. | 752.964 |
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| SMILES | [H][C@]12CCCC[C@@]1([H])C[C@]([H])(N(C[C@@H](O)[C@H](CSc1ccc3ccccc3c1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc3ccccc3n1)C2)C(=O)NC(C)(C)C |
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| Structure | 
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