Ki Summary

Reaction Details

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Target

Bile salt-activated lipase

Ligand

BDBM50286878

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_154779 (CHEMBL873410)

KON

500000.000000 M^-1s^-1

Citation

Lin, G; Liu, HC; Tsai, YC Atropisomeric carbamoyl type inhibitors of pancreatic cholesterol esterase Bioorg Med Chem Lett6:43-46 (1996) Article

More Info.:

Get all data from this article, Assay Method

Bile salt-activated lipase

Name:

Bile salt-activated lipase

Synonyms:

CEL | CEL_BOVIN | Cholesterol esterase

Type:

PROTEIN

Mol. Mass.:

65152.77

Organism:

Bos taurus

Description:

ChEMBL_154778

Residue:

597

Sequence:

LGASRLGPSPGCLAVASAAKLGSVYTEGGFVEGVNKKLSLFGDSIDIFKGIPFAAAPKAL
EKPERHPGWQGTLKAKSFKKRCLQATLTQDSTYGNEDCLYLNIWVPQGRKEVSHDLPVMI
WIYGGAFLMGASQGANFLSNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDSNLPGNY
GLWDQHMAIAWVKRNIEAFGGDPDNITLFGESAGGASVSLQTLSPYNKGLIKRAISQSGV
GLCPWAIQQDPLFWAKRIAEKVGCPVDDTSKMAGCLKITDPRALTLAYKLPLGSTEYPKL
HYLSFVPVIDGDFIPDDPVNLYANAADVDYIAGTNDMDGHLFVGMDVPAINSNKQDVTEE
DFYKLVSGLTVTKGLRGANATYEVYTEPWAQDSSQETRKKTMVDLETDILFLIPTKIAVA
QHKSHAKSANTYTYLFSQPSRMPIYPKWMGADHADDLQYVFGKPFATPLGYRAQDRTVSK
AMIAYWTNFARTGDPNTGHSTVPANWDPYTLEDDNYLEINKQMDSNSMKLHLRTNYLQFW
TQTYQALPTVTSAGASLLPPEDNSQASPVPPADNSGAPTEPSAGDSEVAQMPVVIGF

BDBM50286878

n/a

Name

BDBM50286878

Synonyms:

Butyl-carbamic acid 2'-hydroxy-[1,1']binaphthalenyl-2-yl ester | CHEMBL140853

Type

Small organic molecule

Emp. Form.

C25H23NO3

Mol. Mass.

385.455

SMILES

CCCCNC(=O)Oc1ccc2ccccc2c1-c1c(O)ccc2ccccc12 |(-5.4,-.57,;-4.07,-1.34,;-2.73,-.57,;-1.4,-1.35,;-.06,-.57,;1.27,-1.35,;1.27,-2.89,;2.61,-.58,;3.94,-1.35,;3.94,-2.89,;5.28,-3.66,;6.6,-2.89,;7.93,-3.66,;9.28,-2.89,;9.28,-1.35,;7.95,-.57,;6.6,-1.35,;5.28,-.58,;5.28,.96,;6.6,1.74,;7.93,.97,;6.6,3.28,;5.25,4.05,;3.94,3.26,;2.59,4.03,;1.27,3.26,;1.27,1.72,;2.59,.95,;3.94,1.72,)|

Structure