| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50287332 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_145384 |
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| IC50 | 1.5±n/a nM |
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| Citation |  Hutchinson, I; Archer, S; Hill, KP; Bidlack, JM Synthesis and opioid binding properties of 2-chloroacrylamido derivatives of 7,8-dihydromorphinans Bioorg Med Chem Lett6:1563-1566 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50287332 |
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| n/a |
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| Name | BDBM50287332 |
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| Synonyms: | 1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]-2-chloroacrylamide | CHEMBL289426 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27ClN2O3 |
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| Mol. Mass. | 414.925 |
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| SMILES | Oc1ccc2CC3C4CC[C@@H](NC(=O)C(Cl)=C)[C@@H]5Oc1c2C45CCN3CC1CC1 |TLB:25:24:7:20.4.5,19:20:7:24.22.23| |
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| Structure | 
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