| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
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| Ligand | BDBM50287796 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_39055 (CHEMBL652056) |
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| Ki | 520±n/a nM |
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| Citation |  Fisher, LG; Sher, PM; Skwish, S; Michel, IM; Seiler, SM; Dickinson, KE BMS-187257, a potent, selective, and novel heterocyclic β3 adrenergic receptor agonist Bioorg Med Chem Lett6:2253-2258 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-3 adrenergic receptor |
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| Name: | Beta-3 adrenergic receptor |
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| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43534.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 408 |
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| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
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| BDBM50287796 |
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| n/a |
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| Name | BDBM50287796 |
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| Synonyms: | CHEMBL308150 | ICI-215001 | {4-[2-((S)-2-Hydroxy-3-phenoxy-propylamino)-ethoxy]-phenoxy}-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23NO6 |
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| Mol. Mass. | 361.389 |
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| SMILES | O[C@@H](CNCCOc1ccc(OCC(O)=O)cc1)COc1ccccc1 |
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| Structure | 
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