| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50288148 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_139833 |
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| Ki | 30000±n/a nM |
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| Citation |  Wu, ES; Kover, A; Loch, JT; Rosenberg, LP; Semus, SF; Verhoest, PR; Gordon, JC; Machulskis, AC; McCreedy, SA; Zongrone, J; Blosser, JC Acylhydrazones as M1/M3 selective muscarinic agonists Bioorg Med Chem Lett6:2525-2530 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51390.46 |
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| Organism: | RAT |
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| Description: | P08482 |
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| Residue: | 460 |
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| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50288148 |
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| n/a |
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| Name | BDBM50288148 |
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| Synonyms: | CHEMBL85999 | Phenyl-acetic acid [2,8-dimethyl-1-oxa-8-aza-spiro[4.5]dec-(3E)-ylidene]-hydrazide |
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| Type | Small organic molecule |
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| Emp. Form. | C18H25N3O2 |
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| Mol. Mass. | 315.41 |
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| SMILES | CC1OC2(CC1=NNC(=O)Cc1ccccc1)CCN(C)CC2 |w:6.7| |
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| Structure | 
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