| Reaction Details |
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 | Report a problem with these data |
| Target | Substance-K receptor |
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| Ligand | BDBM50288956 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_142875 |
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| IC50 | 6.7±n/a nM |
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| Citation |  Kersey, ID; Bhogal, N; Donnelly, D; Fishwick, CW; Findlay, JB; Ward, P A Non-peptidic photoactivatable antagonist for mapping the antagonist binding site of the tachykinin NK2 receptor Bioorg Med Chem Lett6:605-608 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Substance-K receptor |
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| Name: | Substance-K receptor |
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| Synonyms: | NK-2 receptor | NK-2R | NK2R | NK2R_HUMAN | NKNAR | Neurokinin 2 receptor | Neurokinin A receptor | Neurokinin NK2 | Neurokinin-2 (NK-2) | Neuromedin-2 receptor (NK-2R) | SKR | TAC2R | TACR2 | Tachykinin receptor 2 | Tachykinin receptor 2 (NK2) | hnk-3 |
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| Type: | Protein |
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| Mol. Mass.: | 44455.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21452 |
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| Residue: | 398 |
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| Sequence: | MGTCDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILA
HRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
IYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATK
CVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLR
HLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST
MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMA
GDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI
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| BDBM50288956 |
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| n/a |
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| Name | BDBM50288956 |
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| Synonyms: | CHEMBL348599 | N-[2-(3,4-Dichloro-phenyl)-4-(4-hydroxy-4-phenyl-piperidin-1-yl)-butyl]-N-methyl-3-(3-trifluoromethyl-3H-diazirin-3-yl)-benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C31H31Cl2F3N4O2 |
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| Mol. Mass. | 619.505 |
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| SMILES | n/a |
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| Structure | 
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