| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
|---|
| Ligand | BDBM50403612 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_205191 |
|---|
| Ki | 120±n/a nM |
|---|
| Citation |  Abell, AD; Brandt, M; Levy, MA; Holt, DA The preparation and evaluation of (+/-)-trans-1-Diazo-8-methoxy-4a-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-2-one as an inhibitor of human type-1 steroid 5α-reductase Bioorg Med Chem Lett6:883-884 (1996) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
|---|
| Name: | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
|---|
| Synonyms: | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 5α-Reductase 1 (5α-R1) | S5A1_HUMAN | S5AR | SR type 1 | SRD5A1 | Steroid 5-alpha-reductase | Steroid 5-alpha-reductase 1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29472.80 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P18405 |
|---|
| Residue: | 259 |
|---|
| Sequence: | MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQE
LPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMA
IMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGD
TGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWY
LRKFEEYPKFRKIIIPFLF
|
|
|
|---|
| BDBM50403612 |
|---|
| n/a |
|---|
| Name | BDBM50403612 |
|---|
| Synonyms: | CHEMBL167774 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H18N2O2 |
|---|
| Mol. Mass. | 270.3263 |
|---|
| SMILES | COc1cccc2c1CC[C@H]1[C-]([N+]#N)C(=O)CC[C@]21C |
|---|
| Structure | 
|
|---|
Search and Browse
