| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine protease 1 |
|---|
| Ligand | BDBM50289562 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_213205 |
|---|
| Ki | 45±n/a nM |
|---|
| Citation |  Préville, P; He, JX; Tarazi, M; Siddiqui, MA; Cody, WL; Doherty, AM An efficient preparation of the potent and selective pseudopeptide thrombin inhibitor, inogatran Bioorg Med Chem Lett7:1563-1566 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine protease 1 |
|---|
| Name: | Serine protease 1 |
|---|
| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 26557.80 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07477 |
|---|
| Residue: | 247 |
|---|
| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
|
|
|
|---|
| BDBM50289562 |
|---|
| n/a |
|---|
| Name | BDBM50289562 |
|---|
| Synonyms: | CHEMBL3216390 | CHEMBL543774 | {(R)-1-Cyclohexylmethyl-2-[(S)-2-(3-guanidino-propylcarbamoyl)-piperidin-1-yl]-2-oxo-ethylamino}-acetic acid; dihydrochloride |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H40Cl2N6O4 |
|---|
| Mol. Mass. | 511.486 |
|---|
| SMILES | Cl.Cl.NC(=N)NCCCNC(=O)[C@@H]1CCCCN1C(=O)[C@@H](CC1CCCCC1)NCC(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
