| Reaction Details |
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 | Report a problem with these data |
| Target | Prolyl endopeptidase |
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| Ligand | BDBM50051539 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_157480 |
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| IC50 | 30±n/a nM |
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| Citation |  Károly, K; Sándor, Es; Edit, S; Miklós, F; Judit, S; Benjámin, P; Andrea, S; István, H Prolyl endopeptidase inhibitors1: N-acyl derivatives of L-thioproline-pyrrolidine Bioorg Med Chem Lett7:1701-1704 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prolyl endopeptidase |
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| Name: | Prolyl endopeptidase |
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| Synonyms: | PPCE_RAT | Prep |
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| Type: | PROTEIN |
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| Mol. Mass.: | 80731.99 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1336163 |
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| Residue: | 710 |
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| Sequence: | MLSFQYPDVYRDETSVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIR
GLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNTLS
DDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFTCMAWTH
DGKGMFYNSYPQQDGKSDGTETSTNLHQKLCYHVLGTDQSEDVLCAEFPDEPKWMGGAEL
SDDGRYVLLSIWEGCDPVNRLWYCDLQQGSNGINGILKWVKLIDNFEGEYDYITNEGTVF
TFKTNRNSPNYRLINIDFTDPDESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLRNVKNI
LQLHDLTTGALLKTFPLDVGSVVGYSGRKKDSEIFYQFTSFLSPGVIYHCDLTREELEPR
VFREVTVKGIDASDYQTIQVFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISI
TPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKE
GYTTSKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKFTIGHAWTTDYG
CSDSKQHFEWLLKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIV
GRSRKQSNPLLIHVDTKAGHGPGKPTAKVIEEVSDMFAFIARCLNIEWIQ
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| BDBM50051539 |
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| n/a |
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| Name | BDBM50051539 |
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| Synonyms: | (S)-4-phenyl-1-(2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl)butan-1-one | 4-Phenyl-1-[(S)-2-(pyrrolidine-1-carbonyl)-pyrrolidin-1-yl]-butan-1-one | 4-Phenyl-1-[2-(pyrrolidine-1-carbonyl)-pyrrolidin-1-yl]-butan-1-one | CHEMBL289651 | SUAM-1221 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H26N2O2 |
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| Mol. Mass. | 314.4219 |
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| SMILES | O=C(CCCc1ccccc1)N1CCC[C@H]1C(=O)N1CCCC1 |r| |
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| Structure | 
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