Reaction Details |
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Target | Peptidylprolyl isomerase |
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Ligand | BDBM50068591 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_66431 |
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Ki | 24±n/a nM |
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Citation | Hamilton, GS; Huang, W; Connolly, MA; Ross, DT; Guo, H; Valentine, HL; Suzdak, PD; Steiner, JP FKBP12-binding domain analogues of FK506 are potent, nonimmunosuppressive neurotrophic agents in vitro and promote recovery in a mouse model of parkinson's disease Bioorg Med Chem Lett7:1785-1790 (1997) Article |
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More Info.: | Get all data from this article, Assay Method |
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Peptidylprolyl isomerase |
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Name: | Peptidylprolyl isomerase |
Synonyms: | FK506 binding protein 12 |
Type: | PROTEIN |
Mol. Mass.: | 11960.67 |
Organism: | Gallus gallus |
Description: | ChEMBL_66431 |
Residue: | 108 |
Sequence: | MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFRFKIGRQEVIKGF
EEGVTQMSLGQRAKLTCTPEMAYGATGHPGVIPPNATLLFDVELLRLE
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BDBM50068591 |
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n/a |
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Name | BDBM50068591 |
Synonyms: | 1-(3,3-Dimethyl-2-oxo-butyryl)-piperidine-2-carboxylic acid 4-(4-methoxy-phenyl)-butyl ester | CHEMBL51710 |
Type | Small organic molecule |
Emp. Form. | C23H33NO5 |
Mol. Mass. | 403.5118 |
SMILES | COc1ccc(CCCCOC(=O)C2CCCCN2C(=O)C(=O)C(C)(C)C)cc1 |
Structure |
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