| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Matrilysin |
|---|
| Ligand | BDBM50063917 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_105802 |
|---|
| IC50 | 20±n/a nM |
|---|
| Citation |  Miller, A; Askew, M; Beckett, RP; Bellamy, CL; Bone, EA; Coates, RE; Davidson, AH; Drummond, AH; Huxley, P; Martin, FM; Saroglou, L; Thompson, AJ; van Dijk, SE; Whittaker, M Inhibition of Matrix Metalloproteinases: An examination of the S1′ pocket Bioorg Med Chem Lett7:193-198 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Matrilysin |
|---|
| Name: | Matrilysin |
|---|
| Synonyms: | MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29681.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P09237 |
|---|
| Residue: | 267 |
|---|
| Sequence: | MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
|
|
|
|---|
| BDBM50063917 |
|---|
| n/a |
|---|
| Name | BDBM50063917 |
|---|
| Synonyms: | (2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide | CHEMBL279785 | cid_119031 | marimastat |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H29N3O5 |
|---|
| Mol. Mass. | 331.4079 |
|---|
| SMILES | CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
