| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50290967 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_145826 |
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| Ki | 0.100000±n/a nM |
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| Citation |  Sabin, V; Horwell, DC; McKnight, AT; Broqua, P trans N-Methyl-N-[2-(1-pyrrolidinyl)cyclohexyl] cycloprop-2-ene-1-carboxamides: Novel lipophilic kappa opioid agonists Bioorg Med Chem Lett7:291-296 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | KOR-1 | Kappa Opioid Receptor | OPIATE Kappa | OPRK_RAT | Opioid receptor | Oprk1 | Ror-d |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42692.90 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P34975 |
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| Residue: | 380 |
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| Sequence: | MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAVLSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRV
RNTVQDPASMRDVGGMNKPV
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| BDBM50290967 |
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| n/a |
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| Name | BDBM50290967 |
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| Synonyms: | 1-{(5R,7S,8S)-8-[(2-Benzofuran-4-yl-acetyl)-methyl-amino]-1-oxa-spiro[4.5]dec-7-yl}-pyrrolidinium | 2-Benzofuran-4-yl-N-methyl-N-((5R,7S,8S)-7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-acetamide | CHEMBL318859 | CI-977 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H32N2O3 |
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| Mol. Mass. | 396.5225 |
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| SMILES | CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1cccc2occc12 |
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| Structure | 
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