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TargetDNA polymerase beta
LigandBDBM50292441
Substrate/Competitorn/a
Meas. Tech.ChEMBL_546495
IC50 2200±n/a nM
Citation Pengsuparp TCai LConstant HFong HHLin LZKinghorn ADPezzuto JMCordell GAIngolfsdöttir KWagner HHughes SH Mechanistic Evaluation of New Plant-Derived Compounds That Inhibit HIV-1 Reverse Transcriptase J Nat Prod 58:1024-1031 (1995) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
DNA polymerase beta
Name:DNA polymerase beta
Synonyms:DNA polymerase beta (Pol β)
Type:Protein
Mol. Mass.:38188.76
Organism:Homo sapiens (Human)
Description:n/a
Residue:335
Sequence:
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
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  Blast E-value cutoff:
BDBM50292441
n/a
NameBDBM50292441
Synonyms:1beta-hydroxyaleuritolic acid 3-p-hydroxybenzoate | 1beta-hydroxyaleuritolic acid-3-p-hydroxybenzoate | CHEMBL454727
TypeSmall organic molecule
Emp. Form.C37H52O6
Mol. Mass.592.8052
SMILESCC1(C)CC[C@@]2(CC=C3[C@]4(C)CC[C@H]5C(C)(C)[C@H](C[C@@H](O)[C@]5(C)[C@H]4CC[C@@]3(C)[C@H]2C1)OC(=O)c1ccc(O)cc1)C(O)=O |r,t:7|
Structure
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