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TargetLuciferin 4-monooxygenase
LigandBDBM50293120
Substrate/Competitorn/a
Meas. Tech.ChEMBL_514919
IC50 3800±n/a nM
Citation Auld DSZhang YQSouthall NTRai GLandsman MMacLure JLangevin DThomas CJAustin CPInglese J A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution. J Med Chem 52:1450-8 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Luciferin 4-monooxygenase
Name:Luciferin 4-monooxygenase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:60658.88
Organism:Photuris pennsylvanica
Description:ChEMBL_514919
Residue:545
Sequence:
MEDKNILYGPEPFHPLADGTAGEQMFYALSRYADISGCIALTNAHTKENVLYEEFLKLSC
RLAESFKKYGLKQNDTIAVCSENGLQFFLPLIASLYLGIIAAPVSDKYIERELIHSLGIV
KPRIIFCSKNTFQKVLNVKSKLKYVETIIILDLNEDLGGYQCLNNFISQNSDINLDVKKF
KPNSFNRDDQVALVMFSSGTTGVSKGVMLTHKNIVARFSHCKDPTFGNAINPTTAILTVI
PFHHGFGMTTTLGYFTCGFRVALMHTFEEKLFLQSLQDYKVESTLLVPTLMAFFPKSALV
EKYDLSHLKEIASGGAPLSKEIGEMVKKRFKLNFVRQGYGLTETTSAVLITPDTDVRPGS
TGKIVPFHAVKVVDPTTGKILGPNETGELYFKGDMIMKSYYNNEEATKAIINKDGWLRSG
DIAYYDNDGHFYIVDRLKSLIKYKGYQVAPAEIEGILLQHPYIVDAGVTGIPDEAAGELP
AAGVVVQTGKYLNEQIVQNFVSSQVSTAKWLRGGVKFLDEIPKGSTGKIDRKVLRQMFEK
HKSKL
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  Blast E-value cutoff:
BDBM50293120
n/a
NameBDBM50293120
Synonyms:2-(3,4-Dimethoxyphenyl)-6-methoxybenzo[d]thiazole | CHEMBL460500
TypeSmall organic molecule
Emp. Form.C16H15NO3S
Mol. Mass.301.36
SMILESCOc1ccc2nc(sc2c1)-c1ccc(OC)c(OC)c1
Structure
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