| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 9 |
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| Ligand | BDBM50293179 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_496947 (CHEMBL1002042) |
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| IC50 | >10000±n/a nM |
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| Citation |  Choong, IC; Serafimova, I; Fan, J; Stockett, D; Chan, E; Cheeti, S; Lu, Y; Fahr, B; Pham, P; Arkin, MR; Walker, DH; Hoch, U A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties. Bioorg Med Chem Lett18:5763-5 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 9 |
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| Name: | Cyclin-dependent kinase 9 |
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| Synonyms: | C-2K | CDC2L4 | CDK9 | CDK9_HUMAN | Cell division cycle 2-like protein kinase 4 | Cell division protein kinase 9 | Cyclin-Dependent Kinase 9 (CDK9) | Cyclin-dependent kinase 9 (CDK9) | Serine/threonine-protein kinase PITALRE | TAK | Tat-associated kinase complex catalytic subunit |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 42789.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 372 |
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| Sequence: | MAKQYDSVECPFCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFP
ITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK
FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNS
QPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLAL
ISQLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDP
AQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNP
ATTNQTEFERVF
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| BDBM50293179 |
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| n/a |
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| Name | BDBM50293179 |
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| Synonyms: | 5-((5-tert-butyloxazol-2-yl)methylthio)-N-cyclohexylthiazol-2-amine | CHEMBL496785 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H25N3OS2 |
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| Mol. Mass. | 351.53 |
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| SMILES | CC(C)(C)c1cnc(CSc2cnc(NC3CCCCC3)s2)o1 |
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| Structure | 
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