| Reaction Details |
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 | Report a problem with these data |
| Target | Neurotensin receptor type 1 |
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| Ligand | BDBM50034787 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_497212 (CHEMBL1003669) |
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| IC50 | 3.79±n/a nM |
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| Citation |  Fan, Y; Lai, MH; Sullivan, K; Popiolek, M; Andree, TH; Dollings, P; Pausch, MH The identification of neurotensin NTS1 receptor partial agonists through a ligand-based virtual screening approach. Bioorg Med Chem Lett18:5789-91 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neurotensin receptor type 1 |
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| Name: | Neurotensin receptor type 1 |
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| Synonyms: | Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46278.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1453811 |
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| Residue: | 418 |
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| Sequence: | MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDI
YSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAM
PVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM
SRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVN
TFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH
GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN
PILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
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| BDBM50034787 |
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| n/a |
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| Name | BDBM50034787 |
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| Synonyms: | 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-methylpentanoic acid | 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-methyl-pentanoic acid | CHEMBL294989 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23NO4 |
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| Mol. Mass. | 353.4116 |
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| SMILES | CC(C)CC(NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O |
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| Structure | 
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