| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM14672 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_571690 (CHEMBL1032138) |
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| pH | 5±n/a |
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| Ki | 490000±n/a nM |
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| Comments | extracted |
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| Citation |  Beck, J; Vercheval, L; Bebrone, C; Herteg-Fernea, A; Lassaux, P; Marchand-Brynaert, J Discovery of novel lipophilic inhibitors of OXA-10 enzyme (class D beta-lactamase) by screening amino analogs and homologs of citrate and isocitrate. Bioorg Med Chem Lett19:3593-7 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | BLAC_BACLI | blaP | penP |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33993.80 |
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| Organism: | Bacillus licheniformis |
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| Description: | ChEMBL_571690 |
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| Residue: | 307 |
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| Sequence: | MKLWFSTLKLKKAAAVLLFSCVALAGCANNQTNASQPAEKNEKTEMKDDFAKLEEQFDAK
LGIFALDTGTNRTVAYRPDERFAFASTIKALTVGVLLQQKSIEDLNQRITYTRDDLVNYN
PITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGPESLKKELRKIGDEVTNPERFE
PELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRELLIDWMKRNTTGDALIRAGVP
DGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSRDKKDAKYDDKLIAEATKVVMK
ALNMNGK
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| BDBM14672 |
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| n/a |
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| Name | BDBM14672 |
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| Synonyms: | 2-hydroxypropane-1,2,3-tricarboxylic acid | CHEMBL1261 | CITRIC ACID | Citrate | Citric Acid | Fragment 2 | cid_311 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H8O7 |
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| Mol. Mass. | 192.1235 |
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| SMILES | OC(=O)CC(O)(CC(O)=O)C(O)=O |
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| Structure | 
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