| Reaction Details |
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 | Report a problem with these data |
| Target | Receptor-type tyrosine-protein phosphatase alpha |
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| Ligand | BDBM50299462 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_590760 (CHEMBL1037598) |
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| Ki | 190000±n/a nM |
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| Citation |  Vidovic, D; Schürer, SC Knowledge-based characterization of similarity relationships in the human protein-tyrosine phosphatase family for rational inhibitor design. J Med Chem52:6649-59 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Receptor-type tyrosine-protein phosphatase alpha |
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| Name: | Receptor-type tyrosine-protein phosphatase alpha |
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| Synonyms: | PTPA | PTPRA | PTPRA_HUMAN | PTPRL2 | Protein-tyrosine phosphatase alpha |
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| Type: | Enzyme |
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| Mol. Mass.: | 90719.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P18433 |
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| Residue: | 802 |
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| Sequence: | MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS
VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP
WEGNSSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY
KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL
FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF
INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW
TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM
LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ
RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL
TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK
DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV
ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ
QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ
YEFCYKVVQEYIDAFSDYANFK
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| BDBM50299462 |
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| n/a |
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| Name | BDBM50299462 |
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| Synonyms: | 2-(3-(dihydroxymethyl)naphthalen-2-ylamino)-2-oxoacetic acid | CHEMBL573989 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H11NO5 |
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| Mol. Mass. | 261.2301 |
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| SMILES | OC(O)c1cc2ccccc2cc1NC(=O)C(O)=O |
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| Structure | 
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