| Reaction Details |
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 | Report a problem with these data |
| Target | Growth factor receptor-bound protein 2 |
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| Ligand | BDBM50300042 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_593416 (CHEMBL1040544) |
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| IC50 | 11±n/a nM |
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| Citation |  Courme, C; Gresh, N; Vidal, M; Lenoir, C; Garbay, C; Florent, JC; Bertounesque, E Synthesis of aryl phosphates based on pyrimidine and triazine scaffolds. Eur J Med Chem45:244-55 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Growth factor receptor-bound protein 2 |
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| Name: | Growth factor receptor-bound protein 2 |
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| Synonyms: | ASH | GRB2 | GRB2 adapter protein | GRB2_HUMAN | Grb2-SH2 | Growth factor receptor-bound protein 2 |
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| Type: | Protein |
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| Mol. Mass.: | 25205.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P62993 |
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| Residue: | 217 |
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| Sequence: | MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
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| BDBM50300042 |
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| n/a |
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| Name | BDBM50300042 |
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| Synonyms: | 4-[(2S)-2-{[(1S)-1-{[(1S)-1,2-dicarbamoylethyl]carbamoyl}-1-{[4-(phosphonooxy)phenyl]methyl}ethyl]carbamoyl}-2-(2-methyl-2-{4-methyl-2-[(E)-2-phenyldiazen-1-yl]phenoxy}propanamido)ethyl]phenoxyphosphonic acid | CHEMBL582892 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H47N7O14P2 |
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| Mol. Mass. | 911.7872 |
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| SMILES | Cc1ccc(OC(C)(C)C(=O)N[C@@H](Cc2ccc(OP(O)(O)=O)cc2)C(=O)N[C@@](C)(Cc2ccc(OP(O)(O)=O)cc2)C(=O)N[C@@H](CC(N)=O)C(N)=O)c(c1)\N=N\c1ccccc1 |r| |
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| Structure | 
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