| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
|---|
| Ligand | BDBM50303530 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_596098 (CHEMBL1040886) |
|---|
| EC50 | 4.4±n/a nM |
|---|
| Citation |  Frost, JM; Dart, MJ; Tietje, KR; Garrison, TR; Grayson, GK; Daza, AV; El-Kouhen, OF; Yao, BB; Hsieh, GC; Pai, M; Zhu, CZ; Chandran, P; Meyer, MD Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity. J Med Chem53:295-315 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 2 |
|---|
| Name: | Cannabinoid receptor 2 |
|---|
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39366.68 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | Q9QZN9 |
|---|
| Residue: | 360 |
|---|
| Sequence: | MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILS
SQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLD
VRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYA
LRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
|
|
|
|---|
| BDBM50303530 |
|---|
| n/a |
|---|
| Name | BDBM50303530 |
|---|
| Synonyms: | (1-(4-Hydroxybutyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone | CHEMBL576706 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H27NO2 |
|---|
| Mol. Mass. | 313.4339 |
|---|
| SMILES | CC1(C)C(C(=O)c2cn(CCCCO)c3ccccc23)C1(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
