| Reaction Details |
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 | Report a problem with these data |
| Target | Alkaline phosphatase, tissue-nonspecific isozyme |
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| Ligand | BDBM50241179 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_604354 (CHEMBL1068637) |
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| pH | 9.8±n/a |
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| Ki | 16000±n/a nM |
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| Comments | extracted |
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| Citation |  Li, L; Chang, L; Pellet-Rostaing, S; Liger, F; Lemaire, M; Buchet, R; Wu, Y Synthesis and evaluation of benzo[b]thiophene derivatives as inhibitors of alkaline phosphatases. Bioorg Med Chem17:7290-300 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alkaline phosphatase, tissue-nonspecific isozyme |
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| Name: | Alkaline phosphatase, tissue-nonspecific isozyme |
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| Synonyms: | ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57306.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1448917 |
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| Residue: | 524 |
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| Sequence: | MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGD
GMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCG
VKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAH
SADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDE
KARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELN
RNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIG
QAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPG
YKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYV
PHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
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| BDBM50241179 |
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| n/a |
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| Name | BDBM50241179 |
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| Synonyms: | (S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole | 6-Phenyl-2,3,5,6-tetrahydro-imidazo[2,1-b]thiazole | 6-Phenyl-2,3,5,6-tetrahydro-imidazo[2,1-b]thiazole (Levamisole) | 6-Phenyl-2,3,5,6-tetrahydro-imidazo[2,1-b]thiazole(Levamisole) | 6-Phenyl-2,3,5,6-tetrahydro-imidazo[2,1-b]thiazole(tetramisole) | CHEMBL1454 | LEVAMISOLE | LEVAMISOLE HYDROCHLORIDE | TCMDC-125847 | cid_68628 | levamisole;6-Phenyl-2,3,5,6-tetrahydro-imidazo[2,1-b]thiazole | tetramisole;6-Phenyl-2,3,5,6-tetrahydro-imidazo[2,1-b]thiazole |
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| Type | Small organic molecule |
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| Emp. Form. | C11H12N2S |
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| Mol. Mass. | 204.291 |
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| SMILES | C1CN2C[C@@H](N=C2S1)c1ccccc1 |r,c:5| |
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| Structure | 
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