| Reaction Details |
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 | Report a problem with these data |
| Target | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
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| Ligand | BDBM50304609 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_606821 (CHEMBL1068585) |
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| Ki | 360000±n/a nM |
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| Citation |  Khan, KM; Fatima, N; Rasheed, M; Jalil, S; Ambreen, N; Perveen, S; Choudhary, MI 1,3,4-Oxadiazole-2(3H)-thione and its analogues: a new class of non-competitive nucleotide pyrophosphatases/phosphodiesterases 1 inhibitors. Bioorg Med Chem17:7816-22 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
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| Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
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| Synonyms: | ENPP1 | ENPP1_HUMAN | M6S1 | NPPS | PC1 | PDNP1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 104934.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1448940 |
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| Residue: | 925 |
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| Sequence: | MERDGCAGGGSRGGEGGRAPREGPAGNGRDRGRSHAAEAPGDPQAAASLLAPMDVGEEPL
EKAARARTAKDPNTYKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFGNC
RCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINY
SSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKK
CGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEW
YKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLP
KDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLIL
ISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSC
REPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNV
FSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVY
TPKHPKEVHPLVQCPFTRNPRDNLGCSCNPSILPIEDFQTQFNLTVAEEKIIKHETLPYG
RPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPL
SPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTL
LRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKD
TSQTPLHCENLDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSF
YQQRKEPVSDILKLKTHLPTFSQED
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| BDBM50304609 |
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| n/a |
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| Name | BDBM50304609 |
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| Synonyms: | 5-[4-t-Butyldimethylsilyloxy phenyl]-1,3,4-oxadiazole-2(3H)-thione | CHEMBL595998 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H20N2O2SSi |
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| Mol. Mass. | 308.471 |
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| SMILES | CC(C)(C)[Si](C)(C)Oc1ccc(cc1)-c1nnc(S)o1 |
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| Structure | 
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