| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
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| Ligand | BDBM50306371 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_609846 (CHEMBL1072787) |
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| EC50 | 237±n/a nM |
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| Citation |  Zhou, C; Tang, C; Chang, E; Ge, M; Lin, S; Cline, E; Tan, CP; Feng, Y; Zhou, YP; Eiermann, GJ; Petrov, A; Salituro, G; Meinke, P; Mosley, R; Akiyama, TE; Einstein, M; Kumar, S; Berger, J; Howard, AD; Thornberry, N; Mills, SG; Yang, L Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists. Bioorg Med Chem Lett20:1298-301 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 1 |
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| Name: | Free fatty acid receptor 1 |
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| Synonyms: | FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 31473.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O14842 |
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| Residue: | 300 |
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| Sequence: | MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
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| BDBM50306371 |
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| n/a |
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| Name | BDBM50306371 |
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| Synonyms: | 5-(4-(4-(trifluoromethyl)pyridin-2-yloxy)benzyl)thiazolidine-2,4-dione | CHEMBL603063 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11F3N2O3S |
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| Mol. Mass. | 368.33 |
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| SMILES | Oc1[nH]c(=O)sc1Cc1ccc(Oc2cc(ccn2)C(F)(F)F)cc1 |
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| Structure | 
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