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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(1B) dopamine receptor | ||
| Ligand | BDBM50004823 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_609908 (CHEMBL1074770) | ||
| Ki | 2±n/a nM | ||
| Citation |  Sasikumar, TK; Burnett, DA; Greenlee, WJ; Smith, M; Fawzi, A; Zhang, H; Lachowicz, JE Remote functionalization of SCH 39166: discovery of potent and selective benzazepine dopamine D1 receptor antagonists. Bioorg Med Chem Lett20:832-5 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(1B) dopamine receptor | |||
| Name: | D(1B) dopamine receptor | ||
| Synonyms: | D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5 | ||
| Type: | Protein | ||
| Mol. Mass.: | 52943.41 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21918 | ||
| Residue: | 477 | ||
| Sequence: |
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| BDBM50004823 | |||
| n/a | |||
| Name | BDBM50004823 | ||
| Synonyms: | (6aS,13bR)-11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol | (6aS,13bR)-11-chloro-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol | 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol | CHEMBL298406 | Ecopipam | SCH 39166 | trans-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H20ClNO | ||
| Mol. Mass. | 313.821 | ||
| SMILES | CN1CCc2cc(Cl)c(O)cc2[C@@H]2[C@@H]1CCc1ccccc21 | ||
| Structure | 
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