| Reaction Details |
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 | Report a problem with these data |
| Target | D(1B) dopamine receptor |
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| Ligand | BDBM50306440 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_609908 (CHEMBL1074770) |
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| Ki | 2.5±n/a nM |
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| Citation |  Sasikumar, TK; Burnett, DA; Greenlee, WJ; Smith, M; Fawzi, A; Zhang, H; Lachowicz, JE Remote functionalization of SCH 39166: discovery of potent and selective benzazepine dopamine D1 receptor antagonists. Bioorg Med Chem Lett20:832-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1B) dopamine receptor |
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| Name: | D(1B) dopamine receptor |
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| Synonyms: | D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5 |
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| Type: | Protein |
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| Mol. Mass.: | 52943.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21918 |
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| Residue: | 477 |
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| Sequence: | MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVL
VCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFD
IMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNW
HRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAI
MIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSV
IMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYA
FNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTP
GNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
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| BDBM50306440 |
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| n/a |
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| Name | BDBM50306440 |
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| Synonyms: | 11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carbaldehyde O-benzyl oxime | CHEMBL599135 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H27ClN2O2 |
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| Mol. Mass. | 446.968 |
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| SMILES | CN1CCc2cc(Cl)c(O)cc2[C@@H]2[C@@H]1CCc1c(\C=N\OCc3ccccc3)cccc21 |r| |
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| Structure | 
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