| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM26596 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_611932 (CHEMBL1071493) |
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| Ki | >100000±n/a nM |
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| Citation |  Katritch, V; Jaakola, VP; Lane, JR; Lin, J; Ijzerman, AP; Yeager, M; Kufareva, I; Stevens, RC; Abagyan, R Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists. J Med Chem53:1799-809 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM26596 |
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| n/a |
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| Name | BDBM26596 |
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| Synonyms: | 3-[(6-amino-9H-purin-8-yl)sulfanyl]propanoic acid | A3NI1, 21 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H9N5O2S |
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| Mol. Mass. | 239.254 |
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| SMILES | Nc1ncnc2nc(SCCC(O)=O)[nH]c12 |
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| Structure | 
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