| Reaction Details |
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 | Report a problem with these data |
| Target | Alkaline phosphatase, germ cell type |
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| Ligand | BDBM50309564 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_610126 (CHEMBL1074491) |
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| IC50 | 600±n/a nM |
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| Citation |  Lanier, M; Sergienko, E; Simão, AM; Su, Y; Chung, T; Millán, JL; Cashman, JR Design and synthesis of selective inhibitors of placental alkaline phosphatase. Bioorg Med Chem18:573-9 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alkaline phosphatase, germ cell type |
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| Name: | Alkaline phosphatase, germ cell type |
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| Synonyms: | ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57374.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_29964 |
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| Residue: | 532 |
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| Sequence: | MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLG
DGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLC
GVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYA
HTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDY
SQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRD
STLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERA
GQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVL
KDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHV
MAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
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| BDBM50309564 |
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| n/a |
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| Name | BDBM50309564 |
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| Synonyms: | 1-(3,4-dihydroxyphenyl)-2-(4,6-dimethylpyrimidin-2-ylthio)ethanone | CHEMBL592869 | cid_715454 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N2O3S |
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| Mol. Mass. | 290.338 |
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| SMILES | Cc1cc(C)nc(SCC(=O)c2ccc(O)c(O)c2)n1 |
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| Structure | 
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