| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
|---|
| Ligand | BDBM10847 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_610124 (CHEMBL1074489) |
|---|
| IC50 | >5000±n/a nM |
|---|
| Citation |  Lanier, M; Sergienko, E; Simão, AM; Su, Y; Chung, T; Millán, JL; Cashman, JR Design and synthesis of selective inhibitors of placental alkaline phosphatase. Bioorg Med Chem18:573-9 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Intestinal-type alkaline phosphatase |
|---|
| Name: | Intestinal-type alkaline phosphatase |
|---|
| Synonyms: | ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56804.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1278525 |
|---|
| Residue: | 528 |
|---|
| Sequence: | MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
|
|
|
|---|
| BDBM10847 |
|---|
| n/a |
|---|
| Name | BDBM10847 |
|---|
| Synonyms: | 1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione | 1,3-dimethyl-7H-purine-2,6-dione | Afonilum | Aminophyllin | Aminophylline | CHEMBL190 | Cardophyllin | Euphylline | Theophy-lline | Theophylline | Theophylline (1,3-dimethylxanthine) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H8N4O2 |
|---|
| Mol. Mass. | 180.164 |
|---|
| SMILES | Cn1c2nc[nH]c2c(=O)n(C)c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
