| Reaction Details |
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 | Report a problem with these data |
| Target | Baculoviral IAP repeat-containing protein 7 |
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| Ligand | BDBM50314475 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_624591 (CHEMBL1111551) |
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| Ki | 44000±n/a nM |
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| Citation |  Cohen, F; Koehler, MF; Bergeron, P; Elliott, LO; Flygare, JA; Franklin, MC; Gazzard, L; Keteltas, SF; Lau, K; Ly, CQ; Tsui, V; Fairbrother, WJ Antagonists of inhibitor of apoptosis proteins based on thiazole amide isosteres. Bioorg Med Chem Lett20:2229-33 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Baculoviral IAP repeat-containing protein 7 |
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| Name: | Baculoviral IAP repeat-containing protein 7 |
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| Synonyms: | BIR3 | BIRC7 | BIRC7_HUMAN | Baculoviral IAP repeat-containing protein 7 | KIAP | LIVIN | MLIAP | RNF50 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32792.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_624591 |
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| Residue: | 298 |
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| Sequence: | MGPKDSAKCLHRGPQPSHWAAGDGPTQERCGPRSLGSPVLGLDTCRAWDHVDGQILGQLR
PLTEEEEEEGAGATLSRGPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQD
KVRCFFCYGGLQSWKRGDDPWTEHAKWFPSCQFLLRSKGRDFVHSVQETHSQLLGSWDPW
EEPEDAAPVAPSVPASGYPELPTPRREVQSESAQEPGGVSPAEAQRAWWVLEPPGARDVE
AQLRRLQEERTCKVCLDRAVSIVFVPCGHLVCAECAPGLQLCPICRAPVRSRVRTFLS
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| BDBM50314475 |
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| n/a |
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| Name | BDBM50314475 |
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| Synonyms: | (S)-N-((S)-1-cyclohexyl-2-((S)-2-(4-(4-fluorophenyl)benzo[d]thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide | CHEMBL1092759 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H35FN4O2S |
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| Mol. Mass. | 522.677 |
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| SMILES | CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1c1nc2c(cccc2s1)-c1ccc(F)cc1 |r| |
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| Structure | 
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