| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50315159 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_624942 (CHEMBL1107065) |
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| EC50 | 2000±n/a nM |
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| Citation |  Wu, Y; Kuntz, JD; Carpenter, AJ; Fang, J; Sauls, HR; Gomez, DJ; Ammala, C; Xu, Y; Hart, S; Tadepalli, S 2,5-Disubstituted pyridines as potent GPR119 agonists. Bioorg Med Chem Lett20:2577-81 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
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| Type: | Protein |
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| Mol. Mass.: | 36901.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDV5 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
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| BDBM50315159 |
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| n/a |
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| Name | BDBM50315159 |
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| Synonyms: | CHEMBL1089837 | furan-2-yl(4-((6-(4-(propylsulfonyl)piperazin-1-yl)pyridin-3-yloxy)methyl)piperidin-1-yl)methanone |
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| Type | Small organic molecule |
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| Emp. Form. | C23H32N4O5S |
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| Mol. Mass. | 476.589 |
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| SMILES | CCCS(=O)(=O)N1CCN(CC1)c1ccc(OCC2CCN(CC2)C(=O)c2ccco2)cn1 |
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| Structure | 
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