| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glutamate receptor 3 |
|---|
| Ligand | BDBM50316377 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_627999 (CHEMBL1105520) |
|---|
| EC50 | 41600±n/a nM |
|---|
| Citation |  Fleming, JJ; England, PM Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. Bioorg Med Chem18:1381-7 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glutamate receptor 3 |
|---|
| Name: | Glutamate receptor 3 |
|---|
| Synonyms: | AMPA-selective glutamate receptor 3 | GLUR3 | GLURC | GRIA3 | GRIA3_HUMAN | GluR-3 | GluR-C | GluR-K3 | Glutamate receptor 3 | Glutamate receptor ionotropic AMPA | Glutamate receptor ionotropic, AMPA 3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 101172.14 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_468627 |
|---|
| Residue: | 894 |
|---|
| Sequence: | MARQKKMGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNT
NQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGAL
HTSFVTPSFPTDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEA
AVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHS
RGYHYMLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKN
APLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKM
VQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSASS
ENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKY
GARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS
KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPP
NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVER
MVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTAD
GVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRNAVNL
AVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMM
VALIEFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI
|
|
|
|---|
| BDBM50316377 |
|---|
| n/a |
|---|
| Name | BDBM50316377 |
|---|
| Synonyms: | (R,S)-6-(2-amino-2-carboxyethyl)-3-hydroxypyridazine 1-oxide | CHEMBL1094977 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H9N3O4 |
|---|
| Mol. Mass. | 199.1641 |
|---|
| SMILES | NC(Cc1ccc(=O)[nH][n+]1[O-])C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
