| Reaction Details |
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 | Report a problem with these data |
| Target | Phospho-N-acetylmuramoyl-pentapeptide-transferase |
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| Ligand | BDBM50318263 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_629295 (CHEMBL1103975) |
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| IC50 | 75000±n/a nM |
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| Citation |  Ii, K; Ichikawa, S; Al-Dabbagh, B; Bouhss, A; Matsuda, A Function-oriented synthesis of simplified caprazamycins: discovery of oxazolidine-containing uridine derivatives as antibacterial agents against drug-resistant bacteria. J Med Chem53:3793-813 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospho-N-acetylmuramoyl-pentapeptide-transferase |
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| Name: | Phospho-N-acetylmuramoyl-pentapeptide-transferase |
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| Synonyms: | MRAY_BACSU | mraY |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35531.14 |
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| Organism: | Bacillus subtilis |
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| Description: | ChEMBL_796247 |
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| Residue: | 324 |
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| Sequence: | MLEQVILFTILMGFLISVLLSPILIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGVMII
LSIIVTTIVMTQKFSEISPEMVLLLFVTLGYGLLGFLDDYIKVVMKRNLGLTSKQKLIGQ
IIIAVVFYAVYHYYNFATDIRIPGTDLSFDLGWAYFILVLFMLVGGSNAVNLTDGLDGLL
SGTAAIAFGAFAILAWNQSQYDVAIFSVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGA
IVTIAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKMSPLHHHYELVGWSEW
RVVVTFWAAGLLLAVLGIYIEVWL
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| BDBM50318263 |
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| n/a |
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| Name | BDBM50318263 |
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| Synonyms: | 5-O-(5-Amino-5-deoxy-beta-D-ribofuranosyl)-6-deoxy-1-6-(4-octylphenylureido)(uracil-1-yl)-beta-D-glycero-L-talo-heptofuranuronicAcid Trifluoroacetic Salt | CHEMBL1095320 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H45N5O12 |
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| Mol. Mass. | 679.7153 |
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| SMILES | CCCCCCCCc1ccc(NC(=O)N[C@@H]([C@H](O[C@@H]2O[C@H](CN)[C@@H](O)[C@H]2O)[C@@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)C(O)=O)cc1 |r| |
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| Structure | 
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