| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin K |
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| Ligand | BDBM50318883 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_633770 (CHEMBL1119720) |
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| IC50 | 34.5±n/a nM |
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| Citation |  Allen, JG; Fotsch, C; Babij, P Emerging targets in osteoporosis disease modification. J Med Chem53:4332-53 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin K |
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| Name: | Cathepsin K |
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| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X |
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| Type: | Enzyme |
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| Mol. Mass.: | 36975.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43235 |
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| Residue: | 329 |
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| Sequence: | MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH
NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD
YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG
YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA
RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
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| BDBM50318883 |
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| n/a |
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| Name | BDBM50318883 |
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| Synonyms: | CHEMBL1085282 | VEL-0230 | sodium(2S,3S)-3-((S)-1-isobutoxy-4-methylpentan-2-ylcarbamoyl)oxirane-2-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C14H24NO5 |
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| Mol. Mass. | 286.3446 |
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| SMILES | CC(C)COC[C@H](CC(C)C)NC(=O)[C@H]1O[C@@H]1C([O-])=O |r| |
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| Structure | 
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