| Reaction Details |
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 | Report a problem with these data |
| Target | Parathyroid hormone/parathyroid hormone-related peptide receptor |
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| Ligand | BDBM50318886 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_633354 (CHEMBL1120574) |
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| EC50 | 3200±n/a nM |
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| Citation |  Allen, JG; Fotsch, C; Babij, P Emerging targets in osteoporosis disease modification. J Med Chem53:4332-53 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Parathyroid hormone/parathyroid hormone-related peptide receptor |
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| Name: | Parathyroid hormone/parathyroid hormone-related peptide receptor |
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| Synonyms: | PTH/PTHr receptor | PTH/PTHrP type I receptor | PTH1 receptor | PTH1R | PTH1R_HUMAN | PTHR | PTHR1 | Parathyroid hormone 1 receptor | Parathyroid hormone receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 66370.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PARATHYROID HT1 0 HUMAN::Q03431 |
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| Residue: | 593 |
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| Sequence: | MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPA
SIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPL
GAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETRE
REVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVK
DAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWIL
VEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK
WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVH
YIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLA
LDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKP
GTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM
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| BDBM50318886 |
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| n/a |
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| Name | BDBM50318886 |
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| Synonyms: | 1,3-dibutyl-5-(diaminomethylene)pyrimidine-2,4,6(1H,3H,5H)-trione | CHEMBL1084168 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H22N4O3 |
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| Mol. Mass. | 282.3388 |
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| SMILES | CCCCN1C(=O)C(C(N)=N)C(=O)N(CCCC)C1=O |
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| Structure | 
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