| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
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| Ligand | BDBM50318995 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_635476 (CHEMBL1117710) |
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| Ki | 1180±n/a nM |
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| Citation |  Tasler, S; Baumgartner, R; Aschenbrenner, A; Ammendola, A; Wolf, K; Wieber, T; Schachtner, J; Blisse, M; Quotschalla, U; Ney, P A vHTS approach for the identification of beta-adrenoceptor ligands. Bioorg Med Chem Lett20:3399-404 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-3 adrenergic receptor |
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| Name: | Beta-3 adrenergic receptor |
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| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43534.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 408 |
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| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
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| BDBM50318995 |
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| n/a |
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| Name | BDBM50318995 |
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| Synonyms: | 2-((1-(3-(4-allyl-2-methoxyphenoxy)-2-hydroxypropyl)piperidin-4-yl)methyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione | CHEMBL1084274 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H34N2O5 |
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| Mol. Mass. | 514.6121 |
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| SMILES | COc1cc(CC=C)ccc1OCC(O)CN1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1 |
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| Structure | 
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